3D Microelectrode Arrays (3D-MEAs)

MultiElectrode Arrays are Consumables for MEASSuRE: View Catalog

BMSEED’s 3D microelectrode arrays (3D-MEAs) are designed for organoid and cell culture research, allowing accurate electrophysiological recording and stimulation on a stretchable silicone substrate. The system includes a 3D pocket to hold organoids, maintaining shape for enhanced physiological relevance and synchronized network measurements. Customizable in size (1-5 mm diameter, 0.8-2 mm depth), the pocket supports various organoid types. For cell cultures, the dual-chamber microfluidics enable co-culturing and media delivery. With customizable electrode layouts, the 3D-MEAs are ideal for advanced applications in neurobiology, mechanotransduction, and tissue engineering.


In Vitro Research


Organoids: sMEA with 3D Pocket

(discounted units available for early adopters)

  • organoid does not remodel in pocket

    • retain organoid shape

    • increased physiological relevance

  • recording from a large surface area of the organoid

    • more accurate network synchronization measurements

    • recording & stimulation of electrophysiological activity

  • silicone substrate & pocket

  • customizable pockets: 1-5 mm diameter, 0.8-2 mm depth

  • customizable electrode layouts

  • product number (PN): 11-53100 (32-channel), 11-53200 (60-channel)

Stretchable microelectrode array with 3D pocket for organoid research

Stretchable microelectrode array with 3D pocket for organoid research

Image (lower left): cerebral organoid in BMSEED’s sMEA with 3D pocket, J. Guo, Emory University


Cell Cultures: sMEA with Dual-Chamber Microfluidics

  • dual-chamber for co-culturing

  • recording & stimulation of extracellular electrophysiological activity

  • elastically stretchable (silicone) substrate & microstructures

  • compatible with perfusion systems to deliver cell media

  • customizable patterns & number of electrodes

  • product number (PN): 11-54100

neurons seeded in BMSEED’s 3D-SW with microchannels

Image: neurons seeded in BMSEED’s 3D-SW with microchannels. A. Palmieri, B.S., Georgia Institute of Technology


Cell Cultures: sMEA with Microchannels for Neural Axon Growth

  • promote structured neuronal networks with axonal guidance to study how neuronal structure correlates to function

  • recording & stimulation of extracellular electrophysiological activity

  • elastically stretchable (silicone) substrate & microstructures

  • customizable patterns & number of electrodes

stretchable microelectrode array with microchannels

Image (right): cortical rat neurons seeded in BMSEED’s sMEA with microchannels, ETH Zurich.


In Vivo Brain Research

Soft and compliant electrodes for electrocorticography (ECoG) in brain research applications


ECoG array with printed circuit board and ZIF clip connector

ECoG Electrode Array

  • 65 microelectrodes + 4 reference electrodes

  • large area & high resolution

  • recording & stimulation of extracellular electrophysiological activity

  • elastically stretchable (silicone substrate)

  • soft

  • product number (PN): 11-56110

View Publication

Pedestal to securely mount the ECoG on the skull without hurting the animal


In Vivo Peripheral Nerve Research

Soft and compliant electrodes for interfaces with the peripheral nervous system (PNS)


PNI with printed circuit board

Peripheral Nerve Interface (PNI)

  • 6 microelectrodes

  • recording & stimulation of extracellular electrophysiological activity

  • elastically stretchable (silicone substrate)

  • soft

  • product number (PN): 11-56210

View Publication

Printed microclip to anchor the PNI to any nerve size without sutures or surgical adhesives

Printed microclip to anchor the PNI to any nerve size without sutures or surgical adhesives


SELECTION GUIDE FOR CONSUMABLE

Identify whether to use stretchable microelectrode arrays, stretchwells, or glass MEAs.