Peer-Reviewed Publications

Welcome to the Publications & Presentations page, where innovation and research come together to shape the future of biomedicine. Here, you’ll find a curated collection of peer-reviewed articles and conference talks showcasing BMSEED's pioneering technologies, including stretchable multielectrode arrays and advanced cell-stretching systems. Explore how our breakthroughs are driving advancements in areas such as neural studies and cardiac models, inspiring collaboration and innovation across the scientific community. Whether you're a researcher, industry professional, or just curious about cutting-edge science, this page offers a window into the transformative power of BMSEED’s work.

In Vitro Applications

NTS-105 decreased cell death and preserved long-term potentiation in an in vitro model of moderate traumatic brain injury

M. K. Dwyer, N. Amelinez-Robles, I. Polsfuss, K. Herbert, C. Kim, N. Varghese, T. J. Parry, B. Buller, T. A. Verdoorn, C. B. Billing Jr, B. Morrison III

Experimental Neurology, 2024, 371, 114608

Stretch‑Induced Injury Affects Cortical Neuronal Networks in a Time‑ and Severity‑Dependent Manner

D. Sullivan, B. J. Vaglio, M. M. Cararo‑Lopes, R. D. Ponce Wong, O. Graudejus, B. L. Firestein

Annals of Biomedical Engineering, 2024, 52(4), 1021-1038

Development and Characterization of Isogenic Cardiac Organoids from Human-Induced Pluripotent Stem Cells Under Supplement Starvation Regimen

A. Patino-Guerrero, R. D. Ponce Wong, V. Kodibagkar, W. Zhu, R. Q. Migrino, O. Graudejus, M. Nikkhah

ACS Biomaterials Science & Engineering, 2023, 9:944-958

A Microclip Peripheral Nerve Interface (μcPNI) for Bioelectronic Interfacing with Small Nerves

C. C. Rowan, O. Graudejus, T. M. Otchy

Advanced Science, 2021, 9(3), 2102945

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A soft and stretchable bilayer electrode array with independent functional layers for the next generation of brain machine interfaces

O. Graudejus, C. Barton, R. D. Ponce Wong, C. C. Rowan, D. Oswalt, B. Greger

Journal of Neural Engineering, 2020, 17(5), 056023

General Science of Our Technology

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The effects of bending on the resistance of elastically stretchable metal conductors, and a comparison with stretching

O. Graudejus, T. Li, J. Cheng, N. Keiper, R. D. Ponce Wong, A. B. Pak, J. Abbas

Applied Physics Letters, 2017, 110, 221906

Alterations in Hippocampal Network Activity after In Vitro Traumatic Brain Injury

W. H. Kang, W. Cao, O. Graudejus, T. Patel, S. Wagner, D. Meaney, B. Morrison III

Journal of Neurotrauma, 2015, 32(13), 1011-1019

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Size dependent rupture strain of elastically stretchable metal conductors

O. Graudejus, Z. Jia, T. Li, S. Wagner

Scripta Materialia, 2012, 66:919-922

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Encapsulating Elastically Stretchable Neural Interfaces: Yield, Resolution, and Recording / Stimulation of Neural Activity

O. Graudejus, B. Morrison, C. Goletiani, Z. Yu, S. Wagner

Advanced Functional Materials, 2012, 22:640-651

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Elastically Stretchable Insulation and Bilevel Metallization and Its Application in a Stretchable RLC Circuit

J. Jones, O. Graudejus, S. Wagner

Journal of Electronic Materials, 2011, 40(6):1335-1344

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Conference Presentations

Controlling the Morphology of Gold Films on Poly(dimethylsiloxane)

O. Graudejus, P. Görrn, S. Wagner

ACS Applied Materials & Interfaces, 2010, 2(7):1927-1933

Determining strain thresholds of calcium dysfunction following biaxial stretch in vitro

I. M. Berke, L. V. Fortuno, A. S. Carrizales, A. DiLeonardi

Society for Neuroscience 2023, Abstract: MEASSuRE-X (TBI Model)

Changes to neural circuit dynamics in neurons after stretch injury as a model of TBI

D. Sullivan, B. Vaglio, R. Ponce Wong, O. Graudejus, B. L. Firestein

Society for Neuroscience 2023, Abstract: MEASSuRE-Premium (TBI Model with Electrophysiology)

Thermal modulation of spontaneous neuronal network activity in vitro

A. S. Carrizales, P. Skelton, I. M. Berke, L. V. Fortuno, A. DiLeonardi

Society for Neuroscience 2023, Abstract: Electrophysiology Module

Expanding the toolkit of biomedical engineers: Stretchable microelectrodes for in vitro and in vivo applications

O. Graudejus

3rd Arizona Symposium in Stem Cell Biology and Regenerative Medicine, 2022, Session A: Tools and Technologies in Regenerative Medicine

NTS-105 Decreases Cell Death After In Vitro Stretch Injury

M. K. Dwyer, C. Kim, N. Varghese, B. Morrison III

Neurotrauma Society Annual Conference 2022, Abstract No. DBA‐11

Plasticity Deficits After In Vitro Stretch Injury on Stretchable Electrode Arrays

M. K. Dwyer, I. Polsfuss, B. Morrison III

48th Northeast Bioengineering Conference, 2022, Symposium Neural Engineering I

Repeated Stimulation and Induction of Long Term Potentiation with Stretchable Microelectrode Arrays (Poster)

M.K. Dwyer, N. Varghese, R. Wong, C. Rowan, O. Graudejus, B. Morrison III

Neurotrauma Society Annual Conference 2021, Abstract No. 10202

Repeated Stimulation and Induction of Long Term Potentiation with Stretchable Microelectrode Arrays (Abstract)

M.K. Dwyer, N. Varghese, R. Wong, C. Rowan, O. Graudejus, B. Morrison III

Neurotrauma Society Annual Conference 2021, Abstract No. 10202

Mechanical Stretch Induces Intracellular Signaling Distinct from LPS-Induced Inflammation in Microglia In Vitro

B. Davies, A. Pybus, B. Guzman, K .Udeshi, O. Graudejus, L. Wood

Neurotrauma Society Annual Conference 2021, Abstract No. 10303

In Vitro Quantitative Analysis of Neuronal Structural and Electrophysiological Changes Following Mechanical Loading

A.M. DiLeonardi, A. Wegener, C. Good

MHSRS TBI Biomarkers: diagnostic and prognostic indicators, 2019, MHSRS-19-02072-Session 2-#567

A.M. DiLeonardi

Journal of Neurotrauma, 2019, 26(13):A04-01

A.M. DiLeonardi, E.A. Matheis, K. Rafaels

Society for Neuroscience Annual Meeting, 2018 Session 056, Brain injury and Trauma: Cellular and Molecular Mechanism I, Poster 056.11

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Flexible and stretchable micro-electrodes for in vitro and in vivo neural interfaces

S. P. Lacour, S. Benmerah, E. Tarte, J. FitzGerald, J. Serra, S. McMahon, J. Fawcett, O. Graudejus, Z. Yu, B Morrison

Medical & Biological Engineering Computation, 2010, 48(10):945-954 (Special Issue)

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Monitoring Hippocampus Electrical Activity In Vitro on an Elastically Deformable Microelectrode Array

Z. Yu, O. Graudejus, C. Tsay, S. P. Lacour, S. Wagner, B. Morrison

Journal of Neurotrauma, 2009, 26(7):1135-1145

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Characterization of an Elastically Stretchable Microelectrode Array and Its Application to Neural Field Potential Recordings

O. Graudejus, Z. Yu, J. Jones, B. Morrison III, S. Wagner

Journal of the Electrochemical Society, 2009, 156(6):P85-P94

In Vivo Applications