In Vitro Research Tools to Better Predict In Vivo Behavior

Predict In Vivo Behavior with Controlled In Vitro Precision.

Improve the predictive accuracy of your pre-clinical research by replicating the in vivo cellular environment in a controlled in vitro setting. Our customizable platform seamlessly combines biomechanics and electrophysiology in a dynamic 3D environment, delivering more relevant and reliable data.

MEASSuRE: 3 methods, 1 tool

MEASSuRE is a complete solution for researchers to stretch cells/tissue mechanically, image them optically, and record/stimulate electrophysiological activity, separately or concurrently.

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Stretchable MicroElectrode Array

Our stretchable MultiElectrode Arrays are incorporated with the MEASSuRE system. They provide the only method for researchers to manipulate chemical, electrical, & mechanical factors independently to more closely replicate the complexity of the human body.

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What Our Customers Say

“Easiness for acquiring electrical signal in a non-invasive manner.”

-A. Patino, Ph.D. Arizona State University

“The most valuable thing is that we can record from cells multiple times…injure and record on the same device.”

-M.K. Dwyer, M.S. Columbia University

“Tuneable parameters and very fast to use.”

-A. Pybus, Ph.D. Georgia Institute of Technology

a) organotypic hippocampal slice cultures (OHSCs), long-term potentiation (LTD) & long-term depression (LTD) induced post-injury; b) primary hippocampal neurons (PHNs) & brain tissue tolerance to traumatic brain injury (TBI); c) organotypic spinal cord slice cultures (OSCSCs) & cypin regulated pain sensitivity after spinal cord injury (SCI); d) human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), hiPSC-CM differentiation; e) neurons, astrocytes, & microglia, pro-inflammatory signaling & immune response to mild traumatic brain injury (mTBI)

Accurate Data

Simulate the cell’s natural environment in the body to generate more relevant in vitro data.

Efficient Workflow

Concurrently apply multiple paradigms with MEASSuRE to save time, money, and research animals.

Unrivaled Results

Better predict clinical outcomes by eliminating drug candidates early & reduce failure rate in clinical trials.

BMSEED Publications

NTS-105 decreased cell death and preserved long-term potentiation in an in vitro model of moderate traumatic brain injury

M. K. Dwyer, N. Amelinez-Robles, I. Polsfuss, K. Herbert, C. Kim, N. Varghese, T. J. Parry, B. Buller, T. A. Verdoorn, C. B. Billing Jr, B. Morrison III

Experimental Neurology, 2024, 371, 114608