Stretchable microelectrode arrays for in vitro biomedical research

View Original

Understanding Neural Activity: The Basis of Brain Function

“New tool offers snapshots of neuron activity” by Anne Trafton from MIT News Office on June 26, 2017

Neural activity refers to the electrical and chemical processes that occur within neurons, the primary cells of the brain and nervous system. These processes are fundamental for everything from basic physiological functions to complex behaviors and thoughts. This blog post will delve into what neural activity is, how it's measured, and why it's essential for understanding human cognition and behavior.



What is Neural Activity?

At its core, neural activity involves the transmission of signals between neurons through specialized connections called synapses. This activity can be categorized into two main types:

“How to measure brain activity in people” by the University of Queensland

  1. Electrical Activity: Neurons generate electrical impulses known as action potentials, which travel along the neuron's axon to the synapse. This electrical signaling is crucial for the rapid transmission of information across different parts of the brain.

  2. Chemical Activity: At the synapse, the action potential triggers the release of neurotransmitters, chemical messengers that cross the synaptic gap to the next neuron, influencing its electrical activity and thus propagating the signal.

Measuring Neural Activity

To understand and study the brain, scientists measure neural activity using various techniques:

  • Electroencephalography (EEG): This method records electrical activity through electrodes placed on the scalp, providing insights into brain states like sleep and wakefulness or diagnosing epilepsy.

  • Functional Magnetic Resonance Imaging (fMRI): fMRI measures changes in blood flow related to neural activity, allowing researchers to identify regions of the brain involved in different tasks.

  • Positron Emission Tomography (PET): PET scans use radioactive tracers to visualize how parts of the brain consume glucose, indicating active areas.

The Importance of Studying Neural Activity

Understanding neural activity is crucial for several reasons:

  • Brain Disorders: Many neurological and psychiatric disorders, such as Alzheimer's disease and schizophrenia, are linked to abnormal neural activity. By studying these patterns, researchers can develop better diagnostic tools and treatments.

  • Cognitive Science: Neural activity is the foundation of sensory processing, learning, memory, and decision-making. Studying these processes helps us understand the biological basis of human cognition and behavior.

  • Brain-Computer Interfaces (BCIs): BCIs rely on decoding neural activity to control external devices, aiding individuals with disabilities and expanding human-machine interaction.

Conclusion

Neural activity is a complex but fascinating subject that offers insights into how our brains work and how we interact with the world. By advancing our understanding of neural processes, we continue to unravel the mysteries of the human mind and develop technologies that can significantly enhance our quality of life. BMSEED explores the use of stretchable MultiElectrode Array technology in EEG designs.

For more detailed information and visuals on neural activity, you can explore these resources:

  1. National Institute of Neurological Disorders and Stroke

  2. An overview of neural activity measurement techniques

Understanding these processes is essential for the advancement of neuroscience and for tackling the challenges presented by neurological diseases.