3D Microelectrode Arrays (3D-MEAs)

Consumables for MEASSuRE: View Catalog


In Vitro Research


Organoids: sMEA with 3D Pocket

(discounted units available for early adopters)

  • organoid does not remodel in pocket

    • retain organoid shape

    • increased physiological relevance

  • recording from a large surface area of the organoid

    • more accurate network synchronization measurements

    • recording & stimulation of electrophysiological activity

  • silicone substrate & pocket

  • customizable pockets: 1-5 mm diameter, 0.8-2 mm depth

  • customizable electrode layouts

Stretchable microelectrode array with 3D pocket for organoid research

Stretchable microelectrode array with 3D pocket for organoid research

Image (lower left): cerebral organoid in BMSEED’s sMEA with 3D pocket, Jidong Guo, Emory University


Cell Cultures: sMEA with Dual-Chamber Microfluidics

  • dual-chamber for co-culturing

  • recording & stimulation of extracellular electrophysiological activity

  • elastically stretchable (silicone) substrate & microstructures

  • compatible with perfusion systems to deliver cell media

  • customizable patterns & number of electrodes

neurons seeded in BMSEED’s 3D-SW with microchannels

Image: neurons seeded in BMSEED’s 3D-SW with microchannels. Abigail Palmieri, B.S., Georgia Institute of Technology


Cell Cultures: sMEA with Microchannels for Neural Axon Growth

  • promote structured neuronal networks with axonal guidance to study how neuronal structure correlates to function

  • recording & stimulation of extracellular electrophysiological activity

  • elastically stretchable (silicone) substrate & microstructures

  • customizable patterns & number of electrodes

stretchable microelectrode array with microchannels

Image (right): cortical rat neurons seeded in BMSEED’s sMEA with microchannels, ETH Zurich.


In Vivo Brain Research

Soft and compliant electrodes for electrocorticography (ECoG) in brain research applications


ECoG Electrode Array

  • 65 microelectrodes + 4 reference electrodes

  • large area & high resolution

  • recording & stimulation of extracellular electrophysiological activity

  • elastically stretchable (silicone substrate)

  • soft

View Publication

ECoG array with printed circuit board and ZIF clip connector

Pedestal to securely mount the ECoG on the skull without hurting the animal

Pedestal to securely mount the ECoG on the skull without hurting the animal


In Vivo Peripheral Nerve Research

Soft and compliant electrodes for interfaces with the peripheral nervous system (PNS)


Peripheral Nerve Interface (PNI)

  • 6 microelectrodes

  • recording & stimulation of extracellular electrophysiological activity

  • elastically stretchable (silicone substrate)

  • soft

View Publication

Printed microclip to anchor the PNI to any nerve size without sutures or surgical adhesives

Printed microclip to anchor the PNI to any nerve size without sutures or surgical adhesives


SELECTION GUIDE FOR CONSUMABLE

Identify whether to use sMEAs, stretchwells, or glass MEAs.